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icaR and icaT are Ancient Chromosome Genes Encoding Substrates of the Type III Secretion Apparatus in Shigella flexneri

ABSTRACT Shigella is an Escherichia coli pathovar that colonizes the cytosol of mucosal cells in the human large intestine. To do this, Shigella uses a Type III Secretion Apparatus (T3SA) to translocate several proteins into host cells. The T3SA and its substrates are encoded by genes of the virulen...

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Principais autores: Navoun Silué, François-Xavier Campbell-Valois
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2022-06-01
Serier:mSphere
Fag:
Escherichia coli
Shigella
type III secretion system
phylogeny
transcription regulation
Online adgang:https://journals.asm.org/doi/10.1128/msphere.00115-22
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