Multi-omics mendelian randomization integrating GWAS and eQTL data revealed potential drug target for irritable bowel syndrome

IntroductionIrritable bowel syndrome (IBS) is a common gastrointestinal disorder mainly affecting the young and female with limited therapeutic options, necessitating the identification of novel drug targets. This study aimed to identify and prioritize new, genetically validated drug targets for IBS...

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Principais autores:	Huiwen Ke, Wenchao Chen, Qian Zhang, Zipeng Liu, Pengfei Wei, Li Li, Haitao Yu, Dongmei Huang, Chaoting Lan, Ning Xu, Lei Pi, Kai Song
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-05-01
Serija:	Frontiers in Genetics
Teme:	drug repurposing eQTL GWAS irritable bowel syndrome mendelian randomization
Online dostop:	https://www.frontiersin.org/articles/10.3389/fgene.2026.1798264/full
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