Increased peak detection accuracy in over-dispersed ChIP-seq data with supervised segmentation models
Abstract Background Histone modification constitutes a basic mechanism for the genetic regulation of gene expression. In early 2000s, a powerful technique has emerged that couples chromatin immunoprecipitation with high-throughput sequencing (ChIP-seq). This technique provides a direct survey of the...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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BMC
2021-06-01
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| Edice: | BMC Bioinformatics |
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| On-line přístup: | https://doi.org/10.1186/s12859-021-04221-5 |
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