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Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations

Abstract Asthma has striking disparities across ancestral groups, but the molecular underpinning of these differences is poorly understood and minimally studied. A goal of the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) is to understand multi-omic signatures of as...

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Principais autores: Brooke Szczesny, Meher Preethi Boorgula, Sameer Chavan, Monica Campbell, Randi K. Johnson, Kai Kammers, Emma E. Thompson, Madison S. Cox, Gautam Shankar, Corey Cox, Andréanne Morin, Wendy Lorizio, Michelle Daya, Samir N. P. Kelada, Terri H. Beaty, Ayo P. Doumatey, Alvaro A. Cruz, Harold Watson, Edward T. Naureckas, B. Louise Giles, Ganiyu A. Arinola, Olumide Sogaolu, Adegoke G. Falade, Nadia N. Hansel, Ivana V. Yang, Christopher O. Olopade, Charles N. Rotimi, R. Clive Landis, Camila A. Figueiredo, Matthew C. Altman, Eimear Kenny, Ingo Ruczinski, Andrew H. Liu, Carole Ober, Margaret A. Taub, Kathleen C. Barnes, Rasika A. Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-05-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-024-48507-7
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