Attenuated levels of hippocampal connexin 43 and its phosphorylation correlate with antidepressant- and anxiolytic-like activities in mice

Clinical and preclinical studies have implicated glial anomalies in major depression. Conversely, evidence suggests that the activity of antidepressant drugs is based, at least in part, on their ability to stimulate density and/or activity of astrocytes, a major glial cell population. Despite this r...

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Detalhes bibliográficos

Principais autores:	Gaël eQuesseveur, Benjamin ePortal, Jean-Arnaud eBasile, Pascal eEzan, Alexia eMathou, Hélène eHalley, Corinne eLeloup, Xavier eFioramonti, Nicole eDéglon, Christian eGiaume, Claire eRampon, Bruno Pierre Guiard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2015-12-01
coleção:	Frontiers in Cellular Neuroscience
Assuntos:	Anxiety Astrocytes Behavior Connexin 43 Depression Hippocampus
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00490/full
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