Unleashing the potential of cell painting assays for compound activities and hazards prediction

The cell painting (CP) assay has emerged as a potent imaging-based high-throughput phenotypic profiling (HTPP) tool that provides comprehensive input data for in silico prediction of compound activities and potential hazards in drug discovery and toxicology. CP enables the rapid, multiplexed investi...

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Hlavní autoři:	Floriane Odje, David Meijer, Elena von Coburg, Justin J. J. van der Hooft, Sebastian Dunst, Marnix H. Medema, Andrea Volkamer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-07-01
Edice:	Frontiers in Toxicology
Témata:	cell painting assay morphological profiling drug development high-throughput screening mode of action bio-activities predictions
On-line přístup:	https://www.frontiersin.org/articles/10.3389/ftox.2024.1401036/full
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