Metabolic pathways within cTfh subsets and glucose-dependent activation of cTfh17 in SLE and healthy individuals
Cellular metabolism plays a key role in T cell biology. Increased glycolysis and mitochondrial respiration have been identified in CD4+ helper T cells from both patients with systemic lupus erythematosus (SLE) and lupus mouse models. Inhibiting this metabolic activity can reduce T cell activation an...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical investigation
2025-07-01
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| Σειρά: | JCI Insight |
| Θέματα: | |
| Διαθέσιμο Online: | https://doi.org/10.1172/jci.insight.189858 |
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