Metformin enhances the therapeutic effects of extracellular vesicles derived from human periodontal ligament stem cells on periodontitis

Abstract Metformin has shown outstanding anti-inflammatory and osteogenic abilities. Mesenchymal stem cell-derived extracellular vesicles (EVs) reveal promising therapeutic potency by carrying various biomolecules. This study explored the effects of metformin on the therapeutic potential of EVs deri...

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Hlavní autoři:	Mingli Xiang, Yulin Liu, Qiushuang Guo, Chengcheng Liao, Linlin Xiao, Meiling Xiang, Xiaoyan Guan, Jianguo Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-08-01
Edice:	Scientific Reports
Témata:	Metformin Extracellular Vesicles PDLSCs Periodontitis Alveolar bone resorption
On-line přístup:	https://doi.org/10.1038/s41598-024-70688-w
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