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A novel ligand on astrocytes interacts with natural cytotoxicity receptor NKp44 regulating immune response mediated by NK cells.

NK cells play important role in immunity against pathogens and cancer. NK cell functions are regulated by inhibitory and activating receptors binding corresponding ligands on the surface of target cells. NK cells were shown to be recruited to the CNS following several pathological conditions. NK cel...

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Збережено в:
Бібліографічні деталі
Автори: Kelly E Bowen, Stephen O Mathew, Kathleen Borgmann, Anuja Ghorpade, Porunelloor A Mathew
Формат: Artigo
Мова:Inglês
Опубліковано: Public Library of Science (PLoS) 2018-01-01
Серія:PLoS ONE
Онлайн доступ:http://europepmc.org/articles/PMC5814005?pdf=render
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