The T120P or M172V mutation on rv2172c confers high level para-aminosalicylic acid resistance in Mycobacterium tuberculosis

Although para-aminosalicylic acid (PAS) has been used to treat tuberculosis for decades, mechanisms of resistance to this drug in Mycobacterium tuberculosis (M. tuberculosis) clinical isolates have not been thoroughly investigated. Previously, we found that decreased methylenetetrahydrofolate reduct...

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Principais autores:	Jin-Tian Xu, Ji-Fang Yu, Tao Cheng, Ao Feng, Ping Yang, Jing Gu, Hong-Jun Yu, Jiao-Yu Deng
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis Group 2024-12-01
סדרה:	Emerging Microbes and Infections
נושאים:	Mycobacterium tuberculosis methylenetetrahydrofolate reductase mutations molecular marker para-aminosalicylic acid resistance
גישה מקוונת:	https://www.tandfonline.com/doi/10.1080/22221751.2024.2374030
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