TRAIL/DR5 pathway promotes AKT phosphorylation, skeletal muscle differentiation, and glucose uptake

Abstract TNF-related apoptosis-inducing ligand (TRAIL) is a protein that induces apoptosis in cancer cells but not in normal ones, where its effects remain to be fully understood. Previous studies have shown that in high-fat diet (HFD)-fed mice, TRAIL treatment reduced body weight gain, insulin resi...

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Principais autores:	Barbara Toffoli, Federica Tonon, Veronica Tisato, Giorgio Zauli, Paola Secchiero, Bruno Fabris, Stella Bernardi
格式:	Artigo
语言:	Inglês
出版:	Nature Publishing Group 2021-11-01
丛编:	Cell Death and Disease
在线阅读:	https://doi.org/10.1038/s41419-021-04383-3
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