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Phase II Trial of First-Line Durvalumab and Chemotherapy in Patients With Extra-Pulmonary Small Cell Carcinoma

Introduction: Prospective randomized trials are lacking in extensive-stage or metastatic extra-pulmonary small cell carcinoma (EPSCC). As a result, treatment for EPSCC is largely extrapolated from SCLC studies. Methods: This single-arm phase II trial enrolled patients with EPSCC to investigate the a...

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Principais autores: Peey-Sei Kok, PhD, Bryan Chan, MMed (Clin Epi), Mason Aberoumand, MAppStat, Alison Zhang, PhD, Ken O’Byrne, MD, Subotheni Thavaneswaran, PhD, Frank Lin, PhD, Maya Kansara, PhD, Theresa Corpuz, BSc (Hons), Patrick Wheeler, BS, Robert John Simes, PhD, David Thomas, PhD, Chee Khoon Lee, PhD
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-07-01
Serier:JTO Clinical and Research Reports
Fag:
Small cell
Durvalumab
Chemo-immunotherapy
Extrapulmonary small cell carcinoma
EPSCC
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666364326000652
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