Loss of β-cell identity and dedifferentiation, not an irreversible process?
Type 2 diabetes (T2D) is a polygenic metabolic disorder characterized by insulin resistance in peripheral tissues and impaired insulin secretion by the pancreas. While the decline in insulin production and secretion was previously attributed to apoptosis of insulin-producing β-cells, recent studies...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2024-06-01
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| Colecção: | Frontiers in Endocrinology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1414447/full |
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