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The sialidase NEU3 promotes pulmonary fibrosis in mice

Abstract Background Sialic acid is often the distal sugar on glycoconjugates, and sialidases are enzymes that remove this sugar. In fibrotic lesions in human and mouse lungs, there is extensive desialylation of glycoconjugates, and upregulation of sialidases including the extracellular sialidase NEU...

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Principais autores: Darrell Pilling, Kyle Sahlberg, Tejas R. Karhadkar, Wensheng Chen, Richard H. Gomer
Format: Artigo
Jezik:Inglês
Izdano: BMC 2022-08-01
Serija:Respiratory Research
Teme:
Online dostop:https://doi.org/10.1186/s12931-022-02146-y
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