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From 2D to 4D: a containerized workflow and browser to explore dynamic chromatin architecture

Abstract Background Characterizing the physical organization of the genome is essential for understanding long-range gene regulation, chromatin compartmentalization, and epigenetic accessibility. Hi-C experiments generate two-dimensional (2D) genome-wide contact maps of chromatin interactions by cap...

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Bibliografische Detailangaben
Hauptverfasser: David H. Rogers, Cullen Roth, Cameron Tauxe, Jeannie T. Lee, Christina R. Steadman, Karissa Y. Sanbonmatsu, Anna Lappala, Shawn R. Starkenburg
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-01-01
Schriftenreihe:BMC Bioinformatics
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Online-Zugang:https://doi.org/10.1186/s12859-025-06361-4
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