Not Just an Alternative Energy Source: Diverse Biological Functions of Ketone Bodies and Relevance of HMGCS2 to Health and Disease

Ketogenesis, a mitochondrial metabolic pathway, occurs primarily in liver, but kidney, colon and retina are also capable of this pathway. It is activated during fasting and exercise, by “keto” diets, and in diabetes as well as during therapy with SGLT2 inhibitors. The principal ketone body is β-hydr...

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Hlavní autoři:	Varshini V. Suresh, Sathish Sivaprakasam, Yangzom D. Bhutia, Puttur D. Prasad, Muthusamy Thangaraju, Vadivel Ganapathy
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-04-01
Edice:	Biomolecules
Témata:	β-hydroxybutyrate ketoacidosis ketone body transporters GPR109A epigenetic modification HMGCS2
On-line přístup:	https://www.mdpi.com/2218-273X/15/4/580
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