Inferring Parameters of the Distribution of Fitness Effects of New Mutations When Beneficial Mutations Are Strongly Advantageous and Rare
Characterizing the distribution of fitness effects (DFE) for new mutations is central in evolutionary genetics. Analysis of molecular data under the McDonald-Kreitman test has suggested that adaptive substitutions make a substantial contribution to between-species divergence. Methods have been propo...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020-07-01
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| Collection: | G3: Genes, Genomes, Genetics |
| Sujets: | |
| Accès en ligne: | http://g3journal.org/lookup/doi/10.1534/g3.120.401052 |
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