Identification of microprotein-coding intronic polyadenylation isoforms and function in genotoxic anticancer drug response

Abstract Background Many transcript isoforms generated by intronic polyadenylation (IPA) encode isoforms of canonical proteins. Microproteins are an emerging class of small proteins translated from small open reading frames (sORFs) in noncoding RNAs and mRNAs, but their production by IPA isoforms is...

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Váldodahkkit:	Alexandre Devaux, Iris Tanaka, Quentin Fouilleul, Amélie Heneman-Masurel, Mandy Cadix, Sophie Michallet, Alina Chakraborty, Céline M. Labbé, Nicolas Fontrodona, Subhadarsini Sahoo, Jean-Baptiste Claude, Marc Deloger, Pierre Gestraud, Ludovic Tessier, Hussein Mortada, Sonia Lameiras, Virginie Raynal, Sylvain Baulande, Nicolas Servant, Didier Auboeuf, Béatrice Eymin, Stéphan Vagner, Martin Dutertre
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2025-10-01
Ráidu:	Genome Biology
Fáttát:	Intronic polyadenylation Alternative last exon DNA-damaging agent Small ORF Micropeptide
Liŋkkat:	https://doi.org/10.1186/s13059-025-03829-7
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