Novel Sulfated Oligosaccharide DP9 from Marine Algae, <i>Gracilaria lemaneiformis</i>: A Potent Galectin-3 Inhibitor for Pancreatic Cancer Therapy

Galectin-3 (Gal-3) is a histologic marker of pancreatic cancer and a potential therapeutic target. This study aimed to characterize a novel sulfated agarose-derived oligosaccharide (DP9) from marine algae, <i>Gracilaria lemaneiformis</i>, evaluate its Gal-3 inhibitory activity, and investigate its a...

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Detalhes bibliográficos

Principais autores:	Pingting Liu, Fengyuan Li, Zhicong Liu, Yang Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-10-01
Colecção:	Marine Drugs
Assuntos:	oligosaccharide DP9 Gal-3 inhibitor pancreatic cancer BxPC-3 cells Gal-3/EGFR/AKT/FOXO3 pathway
Acesso em linha:	https://www.mdpi.com/1660-3397/23/11/423
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