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Short-term calorie restriction enhances DNA repair by non-homologous end joining in mice

Abstract Calorie restriction (CR) improves health, reduces cancer incidence and extends lifespan in multiple organisms including mice. CR was shown to enhance base excision repair and nucleotide excision repair pathways of DNA repair, however, whether CR improves repair of DNA double-strand breaks h...

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Bibliografische Detailangaben
Hauptverfasser: Zhonghe Ke, Denis Firsanov, Brianna Spencer, Andrei Seluanov, Vera Gorbunova
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2020-08-01
Schriftenreihe:npj Aging and Mechanisms of Disease
Online-Zugang:https://doi.org/10.1038/s41514-020-00047-2
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