Letermovir salvage therapy in the management of a case of cytomegalovirus ventriculitis complicated by drug resistance

Reported is a case of cytomegalovirus ventriculitis on a background of HIV infection. Sequencing demonstrated viral mutations conferring resistance to available therapies. Compassionate use of letermovir was attempted; though clinical improvement was observed the patient passed away. Sequencing demo...

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Ngā kaituhi matua:	Andrew Bosworth, Sowsan F. Atabani, Anastasia Theodosiou, Avneet Shahi, Tatiana Peate, Steven Wilson, Emanuela Pelosi, Andrew Rosser
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2020-10-01
Rangatū:	Clinical Infection in Practice
Ngā marau:	Cytomegalovirus Drug resistance Letermovir Immunocompromised Human immunodeficiency virus Clinical virology
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2590170220300261
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!