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Identification of putative target genes of the transcription factor RUNX2.

Comparisons of the genomes of Neandertals and Denisovans with present-day human genomes have suggested that the gene RUNX2, which encodes a transcription factor, may have been positively selected during early human evolution. Here, we overexpress RUNX2 in ten human cell lines and identify genes that...

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Detalles Bibliográficos
Principais autores: Martin Kuhlwilm, Armaity Davierwala, Svante Pääbo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3861491?pdf=render
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