Adipose tissue peroxisomal lipid synthesis orchestrates obesity and insulin resistance through LXR-dependent lipogenesis

Objective: Adipose tissue mass is maintained by a balance between lipolysis and lipid storage. The contribution of adipose tissue lipogenesis to fat mass, especially in the setting of high-fat feeding, is considered minor. Here we investigated the effect of adipose-specific inactivation of the perox...

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Autori principali:	Brian Kleiboeker, Anyuan He, Min Tan, Dongliang Lu, Donghua Hu, Xuejing Liu, Parniyan Goodarzi, Fong-Fu Hsu, Babak Razani, Clay F. Semenkovich, Irfan J. Lodhi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-04-01
Serie:	Molecular Metabolism
Soggetti:	Adipose tissue Cholesterol De novo lipogenesis Diabetes Plasmalogen Liver X receptor
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2212877824000449
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