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An MRTF-A–Sp1–PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy

Cardiac hypertrophy is a critical intermediate step in the pathogenesis of heart failure. A myriad of signaling networks converge on cardiomyocytes to elicit hypertrophic growth in response to various injurious stimuli. In the present study, we investigated the cardiomyocyte-specific role of myocard...

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Principais autores: Teng Wu, Huidi Wang, Xiaojun Xin, Jie Yang, Yannan Hou, Mingming Fang, Xiang Lu, Yong Xu
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020-09-01
Serija:Frontiers in Cell and Developmental Biology
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Online dostop:https://www.frontiersin.org/article/10.3389/fcell.2020.00839/full
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