The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both <it>in vitro </it>and <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Perifosine is a membrane-targeted alkylphospholipid developed to inhibit the PI3K/Akt pathway and has been suggested as a favorable candidate for combined use with radiotherapy. In this study, we investigated the effect of the combined treatment of perifosine and...

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Detalhes bibliográficos

Principais autores:	Zhu Julie, Wang Xiaozhen, Brinkman Kathryn L, Sun Mianen, Ishiyama Hiromichi, Gao Yuanhong, Mai Weiyuan, Huang Ying, Floryk Daniel, Ittmann Michael, Thompson Timothy C, Butler E, Xu Bo, Teh Bin S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2011-04-01
coleção:	Radiation Oncology
Acesso em linha:	http://www.ro-journal.com/content/6/1/39
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