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Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein

Debulking surgery followed by chemotherapy are the standard of care for high-grade serous carcinoma. After an initial good response to treatment, the majority of patients relapse with a chemoresistant profile, leading to a poor overall survival. Chemotherapy regimens used in high-grade serous carcin...

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Bibliografiske detaljer
Principais autores: Mariana Nunes, Patrícia M. A. Silva, Ricardo Coelho, Carla Pinto, Albina Resende, Hassan Bousbaa, Gabriela M. Almeida, Sara Ricardo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-10-01
Serier:Frontiers in Oncology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2021.752127/full
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