Cytokines in the Pathogenesis of Large Granular Lymphocytic Leukemia

Large granular lymphocytic leukemia (LGLL) is a lymphoproliferative disorder of older adults characterized by the clonal expansion of cytotoxic T/natural killer cells due to constitutive pro-survival signaling. In recent years, it has become clear that cytokines and their receptors are aberrantly ex...

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Autors principals:	Colleen Isabelle, Amy Boles, Nitin Chakravarti, Pierluigi Porcu, Jonathan Brammer, Anjali Mishra
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-03-01
Col·lecció:	Frontiers in Oncology
Matèries:	interleukins growth factors cytokines LGLL therapy
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2022.849917/full
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