HSV-2 specifically down regulates HLA-C expression to render HSV-2-infected DCs susceptible to NK cell killing.

Both NK cells and CTLs kill virus-infected and tumor cells. However, the ways by which these killer cells recognize the infected or the tumorigenic cells are different, in fact almost opposite. CTLs are activated through the interaction of the TCR with MHC class I proteins. In contrast, NK cells are...

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Үндсэн зохиолчид:	Moran Elboim, Inna Grodzovski, Esther Djian, Dana G Wolf, Ofer Mandelboim
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2013-03-01
Цуврал:	PLoS Pathogens
Онлайн хандалт:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003226&type=printable
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!