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Non-inferiority of mammalian cell-derived quadrivalent subunit influenza virus vaccines compared to trivalent subunit influenza virus vaccines in healthy children: a phase III randomized, multicenter, double-blind clinical trial

Objectives: The safety and immunogenicity of mammalian cell-derived quadrivalent influenza vaccine (QIVc) as compared with trivalent influenza vaccines (TIV1c/TIV2c) was evaluated in children aged ≥4 to <18 years. Methods: Two thousand three hundred and thirty-three subjects were randomized 2:1:1 to...

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Principais autores: Robyn Hartvickson, Marilou Cruz, John Ervin, Donald Brandon, Eduardo Forleo-Neto, Alemnew F. Dagnew, Richa Chandra, Kelly Lindert, Ahmed Abdul Mateen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-12-01
coleção:International Journal of Infectious Diseases
Assuntos:
Influenza
Vaccine
Quadrivalent
Trivalent
Pediatric
MDCK
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1201971215002647
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