Transarterial chemoembolization combined with tyrosine kinase inhibitors and/or immune checkpoint inhibitors induced hypothyroidism is associated with improved overall survival in hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) treatments, including transarterial chemoembolization (TACE) and systemic therapies (tyrosine kinase inhibitors [TKIs]/immune checkpoint inhibitors [ICIs]) are linked to hypothyroidism. This study aims to elucidate the clinical significance of treatment-induce...

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Hlavní autoři:	Shengyuan Xu, Ruipeng Zheng, Chenghao Sun, Ri Sa
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-05-01
Edice:	Cancer Immunology, Immunotherapy
Témata:	Hypothyroidism Hepatocellular carcinoma Transarterial chemoembolization Tyrosine kinase inhibitors Immune checkpoint inhibitors
On-line přístup:	https://doi.org/10.1007/s00262-025-04073-5
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