An Approach Toward Radioiodination and Radiopharmacological Evaluation of a Carborane-Containing Analog of Indomethacin

Dicarbadodecaboranes (12) (carboranes) are versatile molecular building blocks with unique properties, which allow the expansion of classical medicinal-chemical space. To enable single-photon emission computed tomography (SPECT) imaging of cyclooxygenase-2 (COX-2), we investigated the feasibility of...

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Hauptverfasser:	Jonas Schädlich, Christoph Selg, Cathleen Haase-Kohn, Martin Ullrich, Robert Wodtke, Klaus Kopka, Evamarie Hey-Hawkins, Jens Pietzsch, Markus Laube
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-06-01
Schriftenreihe:	Molecules
Schlagworte:	cyclooxygenase dicarbadodecaborane iodine-123 SPECT imaging
Online-Zugang:	https://www.mdpi.com/1420-3049/31/11/1944
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