Distinct Immune Profiles of Exhausted Effector and Memory CD8+ T Cells in Individuals With Filarial Lymphedema

CD8+ T cells are crucial for the clearance of viral infections, and current research begins to highlight their importance in parasitic diseases too. In-depth research about characteristics of CD8+ T-cell subsets and exhaustion remains uncertain, especially during filariasis, a chronic helminth infec...

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Autori principali:	Sacha Horn, Dennis Borrero-Wolff, Manuel Ritter, Kathrin Arndts, Anna Wiszniewsky, Linda Batsa Debrah, Alexander Y. Debrah, Jubin Osei-Mensah, Mkunde Chachage, Achim Hoerauf, Inge Kroidl, Laura E. Layland
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-08-01
Serie:	Frontiers in Cellular and Infection Microbiology
Soggetti:	Filariae CD8+ T cell exhaustion Wuchereria bancrofti infection lymphatic filariasis immune modulation lymphedema
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcimb.2021.680832/full
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