DNA Methylation Profiles of Purified Cell Types in Bronchoalveolar Lavage: Applications for Mixed Cell Paediatric Pulmonary Studies

In epigenome-wide association studies analysing DNA methylation from samples containing multiple cell types, it is essential to adjust the analysis for cell type composition. One well established strategy for achieving this is reference-based cell type deconvolution, which relies on knowledge of the...

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Bibliografske podrobnosti

Principais autores:	Shivanthan Shanthikumar, Melanie R. Neeland, Richard Saffery, Sarath C. Ranganathan, Alicia Oshlack, Jovana Maksimovic
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-12-01
Serija:	Frontiers in Immunology
Teme:	DNA methylation bronchoalveolar lavage paediatrics cystic fibrosis pulmonary disease epigenetics
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.788705/full
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