TLR4 Deficiency Exacerbates Biliary Injuries and Peribiliary Fibrosis Caused by Clonorchis sinensis in a Resistant Mouse Strain

Mice with different genetic backgrounds have various susceptibilities to infection with Clonorchis sinensis, although the mechanisms underlying are largely unknown. Toll-like receptor 4 (TLR4) as one of the most important pattern recognition receptors (PPRs) is essential for the invasion, survival,...

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Autors principals:	Chao Yan, Jing Wu, Na Xu, Jing Li, Qian-Yang Zhou, Hui-Min Yang, Xiao-Dan Cheng, Ji-Xin Liu, Xin Dong, Stephane Koda, Bei-Bei Zhang, Qian Yu, Jia-Xu Chen, Ren-Xian Tang, Kui-Yang Zheng
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-01-01
Col·lecció:	Frontiers in Cellular and Infection Microbiology
Matèries:	TLR4 Clonorchis sinensis cholangiocytes fibrosis C57BL/10 mice
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcimb.2020.526997/full
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