Molecular mechanisms of bivalirudin-induced cardioprotection in myocardial ischemia–reperfusion injury

Abstract Objective This study aimed to examine the cardioprotective effects of bivalirudin in an in vitro model of hypoxia/reoxygenation (H/R) injury using AC16 human cardiomyocytes, with a focus on elucidating the underlying molecular pathways and key regulatory mechanisms involved. Methods An H/R...

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Hlavní autoři:	Xiu-Fen Li, Gu-Zhuo Shen, Wen-Ding Chen, Remilai Tailaiti, Shi-Shi Tang, Yan Yang, Peng-Fei Gong, Paerhati Tuerxun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-04-01
Edice:	European Journal of Medical Research
Témata:	Bivalirudin In vitro cells Mechanism of action Myocardial ischemia–reperfusion injury Myocardial protection
On-line přístup:	https://doi.org/10.1186/s40001-026-04361-5
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