Clozapine-induced cardiotoxicity in rats: Involvement of tumour necrosis factor alpha, NF-κβ and caspase-3

Clozapine, an ideal antipsychotic drug for the treatment of resistant schizophrenia, is considered the most underutilised treatment for schizophrenia. However, safety concerns have been raised about clozapine-induced cardiotoxicity, which may lead to sudden death, particularly in young patients. The...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Basel A. Abdel-Wahab, Metwally E. Metwally
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2014-01-01
Цуврал:	Toxicology Reports
Нөхцлүүд:	Clozapine Cardiotoxicity Oxidative stress TNF-α DNA damage NF-κB p65 Caspase-3
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2214750014001450
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!