The protein arginine methyltransferase PRMT1 ameliorates cerebral ischemia–reperfusion injury by suppressing RIPK1-mediated necroptosis and apoptosis

Receptor-interacting protein kinase 1 (RIPK1) plays an essential role in regulating the necroptosis and apoptosis in cerebral ischemia-reperfusion (I/R) injury. However, the regulation of RIPK1 kinase activity after cerebral I/R injury remains largely unknown. In this study, we found the downregulat...

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Bibliografische gegevens

Hoofdauteurs:	Tengfei Liu, Gan Huang, Xin Guo, Qiuran Ji, Lu Yu, Runzhe Zong, Yiquan Li, Xiaomeng Song, Qingyi Fu, Qidi Xue, Yi Zheng, Fanshuo Zeng, Ru Sun, Lin Chen, Chengjiang Gao, Huiqing Liu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2025-08-01
Reeks:	Acta Pharmaceutica Sinica B
Onderwerpen:	PRMT1 Cerebral ischemia–reperfusion injury RIPK1 Phosphorylation Arginine methylation Necroptosis
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2211383525004083
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