ProMoHGT: a heterogeneous graph transformer with graph contrastive learning for robust microbial protein function prediction

Abstract Proteins serve as the central executors of life activities, performing diverse functions such as metabolic catalysis, genetic regulation, signal transduction, and cytoskeletal maintenance. However, microbial proteins face unique challenges: their rapid evolution leads to low sequence conser...

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Manylion Llyfryddiaeth

Prif Awduron:	Jianan Sui, Xiaomiao Wang, Yufeng Su, Menglong Gao, Huanjie Huang, Hao Liu, Jianfeng Zhang, Yaohan Tang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2025-12-01
Cyfres:	BMC Genomics
Pynciau:	Microbial protein annotation Heterogeneous graph transformer Graph contrastive learning Multi-source feature integration
Mynediad Ar-lein:	https://doi.org/10.1186/s12864-025-12383-2
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