A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons

Oxysterol analogs that modulate NMDA receptor function are candidates for therapeutic development to treat neuropsychiatric disorders. However, the cellular actions of these compounds are still unclear. For instance, how these compounds are compartmentalized or trafficked in neurons is unknown. In t...

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Principais autores:	Daniel M. Chen, Luke Ziolkowski, Ann Benz, Mingxing Qian, Charles F. Zorumski, Douglas F. Covey, Steven Mennerick
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2018-12-01
סדרה:	Frontiers in Neuroscience
נושאים:	NMDA receptor oxysterol photolabel click chemistry modulation
גישה מקוונת:	https://www.frontiersin.org/article/10.3389/fnins.2018.00923/full
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