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Measuring Single-Cell Calcium Dynamics Using a Myofilament-Localized Optical Biosensor in hiPSC-CMs Derived from DCM Patients

Synchronized contractions of cardiomyocytes within the heart are tightly coupled to electrical stimulation known as excitation-contraction coupling. Calcium plays a key role in this process and dysregulated calcium handling can significantly impair cardiac function and lead to the development of car...

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Wedi'i Gadw mewn:
Prif Awduron: Cara Hawey, Kyla Bourque, Karima Alim, Ida Derish, Elise Rody, Kashif Khan, Natalie Gendron, Renzo Cecere, Nadia Giannetti, Terence E. Hébert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2023-10-01
Cyfres:Cells
Pynciau:
calcium handling
cardiomyocytes
dilated cardiomyopathy
cellular signaling
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/12/21/2526
Tagiau: Ychwanegu Tag
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