Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization

Abstract Background Persistent infection with high-risk Human papillomavirus (HPV), specifically HPV-16, is the leading cause of cervical cancer. Although preventative vaccines have shown significant efficacy in preventing HPV infection, cervical cancer is a significant public health issue that affe...

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Главные авторы:	Bahareh Bahmani, Zahra Amini-bayat, Mohammad Mehdi Ranjbar, Masoud Hassanzadeh Makoui, Amir-Hassan Zarnani
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2025-02-01
Серии:	BMC Infectious Diseases
Предметы:	Human papillomavirus 16-E7 Multi-epitope Therapeutic vaccine design Recombinant protein Cervical cancer
Online-ссылка:	https://doi.org/10.1186/s12879-024-10343-x
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