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Baicalin suppresses Propionibacterium acnes-induced skin inflammation by downregulating the NF-κB/MAPK signaling pathway and inhibiting activation of NLRP3 inflammasome

Acne is a kind of common, chronic skin condition caused by the inflammation of the sebaceous glands in hair follicles. Recent studies have demonstrated that baicalin (BA) possesses potential anti-inflammatory properties. In this study, we evaluated the anti-inflammatory activity of BA in vitro and i...

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Principais autores: Fang Fang, Zeping Xie, Jingyu Quan, Xiaohan Wei, Linlin Wang, Liu Yang
Format: Artigo
Sprog:Inglês
Udgivet: Associação Brasileira de Divulgação Científica
Serier:Brazilian Journal of Medical and Biological Research
Fag:
Acne
Baicalin
NF-κB
MAPK
NLRP3 inflammasome
Online adgang:http://www.scielo.br/pdf/bjmbr/v53n12/1414-431X-bjmbr-53-12-e9949.pdf
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