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Foxo3 regulates cortical and medullary thymic epithelial cell homeostasis with implications in T cell development

Abstract Within the thymus, thymic epithelial cells (TECs) create dedicated microenvironments for T cell development and selection. Considering that TECs are sensitive to distinct pathophysiological conditions, uncovering the molecular elements that coordinate their thymopoietic role has important f...

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Auteurs principaux: Camila Ribeiro, Pedro Ferreirinha, Jonathan J. M. Landry, Fátima Macedo, Laura G. Sousa, Rute Pinto, Vladimir Benes, Nuno L. Alves
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2024-05-01
Collection:Cell Death and Disease
Accès en ligne:https://doi.org/10.1038/s41419-024-06728-0
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