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1,2,3-Triazoles as leaving groups in SNAr–Arbuzov reactions: synthesis of C6-phosphonated purine derivatives

A new method for C–N bond transformations into C–P bonds was developed using 1,2,3-triazoles as leaving groups in SNAr–Arbuzov reactions. A series of C6-phosphonated 2-triazolylpurine derivatives was synthesized for the first time, with the isolated yields reaching up to 82% in the C–P-bond-forming...

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Autori principali: Kārlis-Ēriks Kriķis, Irina Novosjolova, Anatoly Mishnev, Māris Turks
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2021-01-01
Serie:Beilstein Journal of Organic Chemistry
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Accesso online:https://doi.org/10.3762/bjoc.17.19
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