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Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin.

Cellular functions are largely regulated by reversible post-translational modifications of proteins which act as switches. Amongst these, S-palmitoylation is unique in that it confers hydrophobicity. Due to technical difficulties, the understanding of this modification has lagged behind. To investig...

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Detalhes bibliográficos
Principais autores: Tiziano Dallavilla, Laurence Abrami, Patrick A Sandoz, Georgios Savoglidis, Vassily Hatzimanikatis, F Gisou van der Goot
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-02-01
coleção:PLoS Computational Biology
Acesso em linha:https://doi.org/10.1371/journal.pcbi.1004774
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