Increased level of exosomal miR-20b-5p derived from hypothermia-treated microglia promotes neurite outgrowth and synapse recovery after traumatic brain injury

Mild hypothermia has been proven to inhibit microglia activation after TBI. Exosomal microRNA derived from microglia played a critical role in promoting neurite outgrowth and synapse recovery. Here, we aimed to investigate the role of microRNAs in microglial exosomes after hypothermia treatment on n...

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Detalhes bibliográficos

Principais autores:	Chuanfang Wang, Yunxiang Ji, Huabin Zhang, Yongyi Ye, Guilong Zhang, Shizhen Zhang, Chengcheng Zhao, Yezhong Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-04-01
Colecção:	Neurobiology of Disease
Assuntos:	Exosomes Hypothermia Microglia Synapse Traumatic brain injury
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996123000566
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