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MAGIS syndrome: Phenotypes, pathogenesis, and treatmentMAGIS syndrome

The inherited syndromic immunodysregulatory disorder MAGIS demonstrates the central role of Gαi2 regulation of chemotaxis in humans and a novel pathway by which G proteins regulate T cell activation. Here, the authors review MAGIS clinical features, current genetic and biochemical understanding, and...

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Principais autores: Ian T. Lamborn, Huie Jing, Eesha Chattopadhyay, Hyoungjun Ham, Yu Zhang, Helen C. Su
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2025-08-01
coleção:Journal of Human Immunity
Acesso em linha:https://rupress.org/jhi/article-pdf/doi/10.70962/jhi.20250065/1948889/jhi_20250065.pdf
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