Cytosolic nucleic acid sensing as driver of critical illness: mechanisms and advances in therapy
Abstract Nucleic acids from both self- and non-self-sources act as vital danger signals that trigger immune responses. Critical illnesses such as acute respiratory distress syndrome, sepsis, trauma and ischemia lead to the aberrant cytosolic accumulation and massive release of nucleic acids that are...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2025-03-01
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| coleção: | Signal Transduction and Targeted Therapy |
| Acesso em linha: | https://doi.org/10.1038/s41392-025-02174-2 |
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