EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors

Abstract Glioblastoma (GBM) is a typically lethal type of brain tumor with a median survival of 15 months postdiagnosis. This negative prognosis prompted the exploration of alternative treatment options. In particular, the reliance of GBM on angiogenesis triggered the development of anti‐VEGF (vascu...

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Detalhes bibliográficos

Principais autores:	Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David TW Jones, Patrick N Harter, Arne Kienzle, Clarissa Gillmann, Philipp Arnold, Anna Golebiewska, Olivier Keunen, Alf Giese, Andreas von Deimling, Tobias Bäuerle, Simone P Niclou, Michel Mittelbronn, Weilan Ye, Stefan M Pfister, Mirko HH Schmidt
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2018-08-01
Colecção:	EMBO Molecular Medicine
Assuntos:	angiogenesis EGFL7 endothelial cell glioblastoma integrin
Acesso em linha:	https://doi.org/10.15252/emmm.201708420
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