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Topical 5-fluorouracil 1% versus surgical removal as a primary treatment modality for ocular surface squamous neoplasia: a comparison of recurrences and side effects

Abstract Purpose To compare the efficacy and safety of topical 5-fluorouracil (5-FU) 1% eye drops versus surgical removal as a primary treatment modality for ocular surface squamous neoplasia (OSSN). Methods This retrospective cohort study included 11 patients who received 5-FU 1% (5-FU group) and 1...

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Principais autores: Xi Lan, Dongyu Zhang, Shunrong Luo, Xie Fang, Zhiwen Xie, Xianwen Xiao, Yuan Lin, Juan Yang, Xiuxian Qin, Jintao Shi, Aolin Liu, Hongwei Yan, Huping Wu, Zhirong Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-10-01
coleção:BMC Ophthalmology
Assuntos:
Ocular surface squamous neoplasia (OSSN)
5-fluorouracil
Cornea
Carcinoma
Ocular surface
Acesso em linha:https://doi.org/10.1186/s12886-025-04430-z
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